<?xml version="1.0" encoding="UTF-8"?>
<rss version="2.0"
	xmlns:content="http://purl.org/rss/1.0/modules/content/"
	xmlns:wfw="http://wellformedweb.org/CommentAPI/"
	xmlns:dc="http://purl.org/dc/elements/1.1/"
	xmlns:atom="http://www.w3.org/2005/Atom"
	xmlns:sy="http://purl.org/rss/1.0/modules/syndication/"
	xmlns:slash="http://purl.org/rss/1.0/modules/slash/"
	>

<channel>
	<title>JustTheScience &#187; sweeteners</title>
	<atom:link href="http://justthescience.com/archives/tag/sweeteners/feed" rel="self" type="application/rss+xml" />
	<link>http://justthescience.com</link>
	<description>We Do The Research</description>
	<lastBuildDate>Tue, 15 Jun 2010 22:52:40 +0000</lastBuildDate>
	<language>en</language>
	<sy:updatePeriod>hourly</sy:updatePeriod>
	<sy:updateFrequency>1</sy:updateFrequency>
	<generator>http://wordpress.org/?v=</generator>
		<item>
		<title>High Fructose Corn Syrup; good or bad?</title>
		<link>http://justthescience.com/archives/563</link>
		<comments>http://justthescience.com/archives/563#comments</comments>
		<pubDate>Thu, 22 Oct 2009 16:14:14 +0000</pubDate>
		<dc:creator></dc:creator>
				<category><![CDATA[Personal Health]]></category>
		<category><![CDATA[caloric sweeteners]]></category>
		<category><![CDATA[chronic diseases]]></category>
		<category><![CDATA[Coke]]></category>
		<category><![CDATA[diabetes]]></category>
		<category><![CDATA[dietary allowance]]></category>
		<category><![CDATA[ectopic lipid]]></category>
		<category><![CDATA[food]]></category>
		<category><![CDATA[fructose]]></category>
		<category><![CDATA[fruit]]></category>
		<category><![CDATA[HFCS]]></category>
		<category><![CDATA[high fructose corn syrup]]></category>
		<category><![CDATA[insulin]]></category>
		<category><![CDATA[insulin resistance]]></category>
		<category><![CDATA[metabolic]]></category>
		<category><![CDATA[milk]]></category>
		<category><![CDATA[obesity]]></category>
		<category><![CDATA[satiety]]></category>
		<category><![CDATA[short-term metabolic effects]]></category>
		<category><![CDATA[sucrose]]></category>
		<category><![CDATA[sweeteners]]></category>
		<category><![CDATA[westernization]]></category>

		<guid isPermaLink="false">http://justthescience.com/?p=563</guid>
		<description><![CDATA[As levels of diabetes, obesity, and other dietary issues increase (diabetes alone has increased 763% from 1935 to 1996 in the united states (Gross et al 2004)) studies have been conducted to investigate whether the 1,000% rise in the use of High Fructose Corn Syrup (HFCS) from 1967 to 2000 in the American food industry [...]]]></description>
			<content:encoded><![CDATA[<p>As levels of diabetes, obesity, and other dietary issues increase (diabetes alone has increased 763% from 1935 to 1996 in the united states (Gross <em>et al</em> 2004)) studies have been conducted to investigate whether the 1,000% rise in the use of High Fructose Corn Syrup (HFCS) from 1967 to 2000 in the American food industry is a major contributor (Bray <em>et al</em> 2004).<sup><a href="http://justthescience.com/archives/563#footnote_0_563" id="identifier_0_563" class="footnote-link footnote-identifier-link" title="Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity">1</a></sup>  <sup><a href="http://justthescience.com/archives/563#footnote_1_563" id="identifier_1_563" class="footnote-link footnote-identifier-link" title="Fructose, insulin resistance, and metabolic dyslipidemia">2</a></sup> In this article, we will examine whether or not HFCS is truly a factor in this significant increase.</p>
<p>Early studies found that there were possible clinical explanations for metabolic differences derived from HFCS ingestion and other sweeteners; primarily that it did not trigger insulin creation and thereby was thought to not trigger satiety signals (Reiser <em>et al</em> 1989) (Elliott <em>et al</em> 2002) (Bray <em>et al</em> 2004) (Teff <em>et al</em> 2004) .<sup><a href="http://justthescience.com/archives/563#footnote_2_563" id="identifier_2_563" class="footnote-link footnote-identifier-link" title="Fructose, weight gain, and the insulin resistance syndrome">3</a></sup> <sup><a href="http://justthescience.com/archives/563#footnote_3_563" id="identifier_3_563" class="footnote-link footnote-identifier-link" title="Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity">4</a></sup> <sup><a href="http://justthescience.com/archives/563#footnote_4_563" id="identifier_4_563" class="footnote-link footnote-identifier-link" title="Dietary Fructose Reduces Circulating Insulin and Leptin, Attenuates Postprandial Suppression of Ghrelin, and Increases Triglycerides in Women">5</a></sup> <sup><a href="http://justthescience.com/archives/563#footnote_5_563" id="identifier_5_563" class="footnote-link footnote-identifier-link" title="Day-long glucose, insulin, and fructose responses of hyperinsulinemic and nonhyperinsulinemic men adapted to diets containing either fructose or high-amylose cornstarch">6</a></sup>  However, more recent studies have found no difference in resulting satiety in men or women resulting from HFCS, sucrose, or milk, (Soenen and Westerterp-Plantenga 2007) (Melanson <em>et al 2008)</em> (Akhavan and Anderson 2007),<sup><a href="http://justthescience.com/archives/563#footnote_6_563" id="identifier_6_563" class="footnote-link footnote-identifier-link" title="No differences in satiety or energy intake after high-fructose corn syrup, sucrose, or milk preloads">7</a></sup> <sup><a href="http://justthescience.com/archives/563#footnote_7_563" id="identifier_7_563" class="footnote-link footnote-identifier-link" title="High-fructose corn syrup, energy intake, and appetite regulation">8</a></sup> <sup><a href="http://justthescience.com/archives/563#footnote_8_563" id="identifier_8_563" class="footnote-link footnote-identifier-link" title="Effects of glucose-to-fructose ratios in solutions on subjective satiety, food intake, and satiety hormones in young men">9</a></sup> and that HFCS yields similar metabolic responses to other caloric sweeteners. (Angelopoulos <em>et al</em> 2009),<sup><a href="http://justthescience.com/archives/563#footnote_9_563" id="identifier_9_563" class="footnote-link footnote-identifier-link" title="The Effect of High-Fructose Corn Syrup Consumption on Triglycerides and Uric Acid">10</a></sup> Stanhope <em>et al</em> 2008 and Melanson  <em>et al</em> 2007 determined that sucrose and HFCS do not have significantly different short-term metabolic effects,<sup><a href="http://justthescience.com/archives/563#footnote_10_563" id="identifier_10_563" class="footnote-link footnote-identifier-link" title="Twenty-four-hour endocrine and metabolic profiles following consumption of high-fructose corn syrup-, sucrose-, fructose-, and glucose-sweetened beverages with meals">11</a></sup> <sup><a href="http://justthescience.com/archives/563#footnote_11_563" id="identifier_11_563" class="footnote-link footnote-identifier-link" title="Effects of high-fructose corn syrup and sucrose consumption on circulating glucose, insulin, leptin, and ghrelin and on appetite in normal-weight women">12</a></sup> and moderate levels (~1.5 grams of fructose per kilogram of body mass) of HFCS intake  does not cause ectopic lipid deposition or insulin resistance in healthy humans (Le <em>et al</em> 2006).<sup><a href="http://justthescience.com/archives/563#footnote_12_563" id="identifier_12_563" class="footnote-link footnote-identifier-link" title="A 4-wk high-fructose diet alters lipid metabolism without affecting insulin sensitivity or ectopic lipids in healthy humans">13</a></sup></p>
<p>Although HFCS is not itself responsible for the increase in dietary and metabolic disorders, other studies have demonstrated that increasing levels of excess energy consumption in general is a cause (Gross <em>et al</em> 2004).<sup><a href="http://justthescience.com/archives/563#footnote_13_563" id="identifier_13_563" class="footnote-link footnote-identifier-link" title="Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment">14</a></sup>  For thousands of years humans consumed fructose amounting to 16–20 grams per day, largely from fresh fruits (Gross <em>et al</em> 2004). <sup><a href="http://justthescience.com/archives/563#footnote_14_563" id="identifier_14_563" class="footnote-link footnote-identifier-link" title="Fructose, insulin resistance, and metabolic dyslipidemia">15</a></sup> Westernization of diets has resulted in significant increases in food with added fructose, leading to typical daily consumptions amounting to 85–100 grams of fructose per day (Gross <em>et al</em> 2004). <sup><a href="http://justthescience.com/archives/563#footnote_15_563" id="identifier_15_563" class="footnote-link footnote-identifier-link" title="Fructose, insulin resistance, and metabolic dyslipidemia">16</a></sup>  For example, a 12 ounce Coke contains 39 grams of fructose and the USDA Recommended Daily Allowance allots for 32 grams of carbohydrates in a 2,000 calorie diet.<sup><a href="http://justthescience.com/archives/563#footnote_16_563" id="identifier_16_563" class="footnote-link footnote-identifier-link" title="Carbohydrates">17</a></sup>  A single 12 ounce Coke therefore contains significantly more than an individual&#8217;s entire excess dietary energy allowance for a day.  Raben <em>et al </em>2002 found that people have a very difficult time compensating for increased levels of calories associated with increased sugar intake by lowering caloric intake elsewhere.<sup><a href="http://justthescience.com/archives/563#footnote_17_563" id="identifier_17_563" class="footnote-link footnote-identifier-link" title="Sucrose compared with artificial sweeteners: different effects on ad libitum food intake and body weight after 10 wk of supplementation in overweight subjects">18</a></sup>  While moderate ingestion of HFCS will not specifically cause harm to oneself, it is advisable to monitor and limit consumption as much as possible.</p>
<ol class="footnotes"><li id="footnote_0_563" class="footnote"><a href="http://www.ajcn.cnfindpark.cn/cgi/content/abstract/79/4/537">Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity</a></li><li id="footnote_1_563" class="footnote"><a href="http://www.nutritionandmetabolism.com/content/2/1/5" target="_blank">Fructose, insulin resistance, and metabolic dyslipidemia</a></li><li id="footnote_2_563" class="footnote"><a href="http://www.ajcn.org/cgi/content/abstract/76/5/911">Fructose, weight gain, and the insulin resistance syndrome</a></li><li id="footnote_3_563" class="footnote"><a href="http://www.ajcn.cnfindpark.cn/cgi/content/abstract/79/4/537">Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity</a></li><li id="footnote_4_563" class="footnote"><a href="http://jcem.endojournals.org/cgi/content/abstract/89/6/2963">Dietary Fructose Reduces Circulating Insulin and Leptin, Attenuates Postprandial Suppression of Ghrelin, and Increases Triglycerides in Women</a></li><li id="footnote_5_563" class="footnote"><a href="http://www.ajcn.org/cgi/content/abstract/50/5/1008">Day-long glucose, insulin, and fructose responses of hyperinsulinemic and nonhyperinsulinemic men adapted to diets containing either fructose or high-amylose cornstarch</a></li><li id="footnote_6_563" class="footnote"><a href="http://www.ajcn.org/cgi/content/abstract/86/6/1586">No differences in satiety or energy intake after high-fructose corn syrup, sucrose, or milk preloads</a></li><li id="footnote_7_563" class="footnote"><a href="http://www.ajcn.org/cgi/content/abstract/88/6/1738S?ijkey=51a6eb2a2a2308a265762245d4dc6f538a555c36&amp;keytype2=tf_ipsecsha">High-fructose corn syrup, energy intake, and appetite regulation</a></li><li id="footnote_8_563" class="footnote"><a href="http://www.ajcn.cnfindpark.cn/cgi/content/abstract/86/5/1354">Effects of glucose-to-fructose ratios in solutions on subjective satiety, food intake, and satiety hormones in young men</a></li><li id="footnote_9_563" class="footnote"><a href="http://jn.nutrition.org/cgi/content/abstract/139/6/1242S">The Effect of High-Fructose Corn Syrup Consumption on Triglycerides and Uric Acid</a></li><li id="footnote_10_563" class="footnote"><a href="http://ajcn.cnfindpark.cn/cgi/content/abstract/87/5/1194">Twenty-four-hour endocrine and metabolic profiles following consumption of high-fructose corn syrup-, sucrose-, fructose-, and glucose-sweetened beverages with meals</a></li><li id="footnote_11_563" class="footnote"><a href="http://www.ncbi.nlm.nih.gov/pubmed/17234503">Effects of high-fructose corn syrup and sucrose consumption on circulating glucose, insulin, leptin, and ghrelin and on appetite in normal-weight women</a></li><li id="footnote_12_563" class="footnote"><a href="http://cat.inist.fr/?aModele=afficheN&amp;cpsidt=18373945">A 4-wk high-fructose diet alters lipid metabolism without affecting insulin sensitivity or ectopic lipids in healthy humans</a></li><li id="footnote_13_563" class="footnote"><a href="http://www.ajcn.org/cgi/content/full/79/5/774?ijkey=cJSxz0rjkfs9s&amp;keytype=ref&amp;siteid=ajcn">Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment</a></li><li id="footnote_14_563" class="footnote"><a href="http://www.nutritionandmetabolism.com/content/2/1/5" target="_blank">Fructose, insulin resistance, and metabolic dyslipidemia</a></li><li id="footnote_15_563" class="footnote"><a href="http://www.nutritionandmetabolism.com/content/2/1/5#B7">Fructose, insulin resistance, and metabolic dyslipidemia</a></li><li id="footnote_16_563" class="footnote"><a href="http://www.health.gov/dietaryguidelines/dga2005/document/html/chapter7.htm" target="_blank">Carbohydrates</a></li><li id="footnote_17_563" class="footnote"><a href="http://www.ncbi.nlm.nih.gov/pubmed/12324283?dopt=Abstract&amp;holding=f1000,f1000m,isrctn">Sucrose compared with artificial sweeteners: different effects on ad libitum food intake and body weight after 10 wk of supplementation in overweight subjects</a></li></ol>]]></content:encoded>
			<wfw:commentRss>http://justthescience.com/archives/563/feed</wfw:commentRss>
		<slash:comments>1</slash:comments>
		</item>
	</channel>
</rss>

