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	<title>JustTheScience &#187; sucrose</title>
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	<description>We Do The Research</description>
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		<title>High Fructose Corn Syrup; good or bad?</title>
		<link>http://justthescience.com/archives/563</link>
		<comments>http://justthescience.com/archives/563#comments</comments>
		<pubDate>Thu, 22 Oct 2009 16:14:14 +0000</pubDate>
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				<category><![CDATA[Personal Health]]></category>
		<category><![CDATA[caloric sweeteners]]></category>
		<category><![CDATA[chronic diseases]]></category>
		<category><![CDATA[Coke]]></category>
		<category><![CDATA[diabetes]]></category>
		<category><![CDATA[dietary allowance]]></category>
		<category><![CDATA[ectopic lipid]]></category>
		<category><![CDATA[food]]></category>
		<category><![CDATA[fructose]]></category>
		<category><![CDATA[fruit]]></category>
		<category><![CDATA[HFCS]]></category>
		<category><![CDATA[high fructose corn syrup]]></category>
		<category><![CDATA[insulin]]></category>
		<category><![CDATA[insulin resistance]]></category>
		<category><![CDATA[metabolic]]></category>
		<category><![CDATA[milk]]></category>
		<category><![CDATA[obesity]]></category>
		<category><![CDATA[satiety]]></category>
		<category><![CDATA[short-term metabolic effects]]></category>
		<category><![CDATA[sucrose]]></category>
		<category><![CDATA[sweeteners]]></category>
		<category><![CDATA[westernization]]></category>

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		<description><![CDATA[As levels of diabetes, obesity, and other dietary issues increase (diabetes alone has increased 763% from 1935 to 1996 in the united states (Gross et al 2004)) studies have been conducted to investigate whether the 1,000% rise in the use of High Fructose Corn Syrup (HFCS) from 1967 to 2000 in the American food industry [...]]]></description>
			<content:encoded><![CDATA[<p>As levels of diabetes, obesity, and other dietary issues increase (diabetes alone has increased 763% from 1935 to 1996 in the united states (Gross <em>et al</em> 2004)) studies have been conducted to investigate whether the 1,000% rise in the use of High Fructose Corn Syrup (HFCS) from 1967 to 2000 in the American food industry is a major contributor (Bray <em>et al</em> 2004).<sup><a href="http://justthescience.com/archives/563#footnote_0_563" id="identifier_0_563" class="footnote-link footnote-identifier-link" title="Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity">1</a></sup>  <sup><a href="http://justthescience.com/archives/563#footnote_1_563" id="identifier_1_563" class="footnote-link footnote-identifier-link" title="Fructose, insulin resistance, and metabolic dyslipidemia">2</a></sup> In this article, we will examine whether or not HFCS is truly a factor in this significant increase.</p>
<p>Early studies found that there were possible clinical explanations for metabolic differences derived from HFCS ingestion and other sweeteners; primarily that it did not trigger insulin creation and thereby was thought to not trigger satiety signals (Reiser <em>et al</em> 1989) (Elliott <em>et al</em> 2002) (Bray <em>et al</em> 2004) (Teff <em>et al</em> 2004) .<sup><a href="http://justthescience.com/archives/563#footnote_2_563" id="identifier_2_563" class="footnote-link footnote-identifier-link" title="Fructose, weight gain, and the insulin resistance syndrome">3</a></sup> <sup><a href="http://justthescience.com/archives/563#footnote_3_563" id="identifier_3_563" class="footnote-link footnote-identifier-link" title="Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity">4</a></sup> <sup><a href="http://justthescience.com/archives/563#footnote_4_563" id="identifier_4_563" class="footnote-link footnote-identifier-link" title="Dietary Fructose Reduces Circulating Insulin and Leptin, Attenuates Postprandial Suppression of Ghrelin, and Increases Triglycerides in Women">5</a></sup> <sup><a href="http://justthescience.com/archives/563#footnote_5_563" id="identifier_5_563" class="footnote-link footnote-identifier-link" title="Day-long glucose, insulin, and fructose responses of hyperinsulinemic and nonhyperinsulinemic men adapted to diets containing either fructose or high-amylose cornstarch">6</a></sup>  However, more recent studies have found no difference in resulting satiety in men or women resulting from HFCS, sucrose, or milk, (Soenen and Westerterp-Plantenga 2007) (Melanson <em>et al 2008)</em> (Akhavan and Anderson 2007),<sup><a href="http://justthescience.com/archives/563#footnote_6_563" id="identifier_6_563" class="footnote-link footnote-identifier-link" title="No differences in satiety or energy intake after high-fructose corn syrup, sucrose, or milk preloads">7</a></sup> <sup><a href="http://justthescience.com/archives/563#footnote_7_563" id="identifier_7_563" class="footnote-link footnote-identifier-link" title="High-fructose corn syrup, energy intake, and appetite regulation">8</a></sup> <sup><a href="http://justthescience.com/archives/563#footnote_8_563" id="identifier_8_563" class="footnote-link footnote-identifier-link" title="Effects of glucose-to-fructose ratios in solutions on subjective satiety, food intake, and satiety hormones in young men">9</a></sup> and that HFCS yields similar metabolic responses to other caloric sweeteners. (Angelopoulos <em>et al</em> 2009),<sup><a href="http://justthescience.com/archives/563#footnote_9_563" id="identifier_9_563" class="footnote-link footnote-identifier-link" title="The Effect of High-Fructose Corn Syrup Consumption on Triglycerides and Uric Acid">10</a></sup> Stanhope <em>et al</em> 2008 and Melanson  <em>et al</em> 2007 determined that sucrose and HFCS do not have significantly different short-term metabolic effects,<sup><a href="http://justthescience.com/archives/563#footnote_10_563" id="identifier_10_563" class="footnote-link footnote-identifier-link" title="Twenty-four-hour endocrine and metabolic profiles following consumption of high-fructose corn syrup-, sucrose-, fructose-, and glucose-sweetened beverages with meals">11</a></sup> <sup><a href="http://justthescience.com/archives/563#footnote_11_563" id="identifier_11_563" class="footnote-link footnote-identifier-link" title="Effects of high-fructose corn syrup and sucrose consumption on circulating glucose, insulin, leptin, and ghrelin and on appetite in normal-weight women">12</a></sup> and moderate levels (~1.5 grams of fructose per kilogram of body mass) of HFCS intake  does not cause ectopic lipid deposition or insulin resistance in healthy humans (Le <em>et al</em> 2006).<sup><a href="http://justthescience.com/archives/563#footnote_12_563" id="identifier_12_563" class="footnote-link footnote-identifier-link" title="A 4-wk high-fructose diet alters lipid metabolism without affecting insulin sensitivity or ectopic lipids in healthy humans">13</a></sup></p>
<p>Although HFCS is not itself responsible for the increase in dietary and metabolic disorders, other studies have demonstrated that increasing levels of excess energy consumption in general is a cause (Gross <em>et al</em> 2004).<sup><a href="http://justthescience.com/archives/563#footnote_13_563" id="identifier_13_563" class="footnote-link footnote-identifier-link" title="Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment">14</a></sup>  For thousands of years humans consumed fructose amounting to 16–20 grams per day, largely from fresh fruits (Gross <em>et al</em> 2004). <sup><a href="http://justthescience.com/archives/563#footnote_14_563" id="identifier_14_563" class="footnote-link footnote-identifier-link" title="Fructose, insulin resistance, and metabolic dyslipidemia">15</a></sup> Westernization of diets has resulted in significant increases in food with added fructose, leading to typical daily consumptions amounting to 85–100 grams of fructose per day (Gross <em>et al</em> 2004). <sup><a href="http://justthescience.com/archives/563#footnote_15_563" id="identifier_15_563" class="footnote-link footnote-identifier-link" title="Fructose, insulin resistance, and metabolic dyslipidemia">16</a></sup>  For example, a 12 ounce Coke contains 39 grams of fructose and the USDA Recommended Daily Allowance allots for 32 grams of carbohydrates in a 2,000 calorie diet.<sup><a href="http://justthescience.com/archives/563#footnote_16_563" id="identifier_16_563" class="footnote-link footnote-identifier-link" title="Carbohydrates">17</a></sup>  A single 12 ounce Coke therefore contains significantly more than an individual&#8217;s entire excess dietary energy allowance for a day.  Raben <em>et al </em>2002 found that people have a very difficult time compensating for increased levels of calories associated with increased sugar intake by lowering caloric intake elsewhere.<sup><a href="http://justthescience.com/archives/563#footnote_17_563" id="identifier_17_563" class="footnote-link footnote-identifier-link" title="Sucrose compared with artificial sweeteners: different effects on ad libitum food intake and body weight after 10 wk of supplementation in overweight subjects">18</a></sup>  While moderate ingestion of HFCS will not specifically cause harm to oneself, it is advisable to monitor and limit consumption as much as possible.</p>
<ol class="footnotes"><li id="footnote_0_563" class="footnote"><a href="http://www.ajcn.cnfindpark.cn/cgi/content/abstract/79/4/537">Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity</a></li><li id="footnote_1_563" class="footnote"><a href="http://www.nutritionandmetabolism.com/content/2/1/5" target="_blank">Fructose, insulin resistance, and metabolic dyslipidemia</a></li><li id="footnote_2_563" class="footnote"><a href="http://www.ajcn.org/cgi/content/abstract/76/5/911">Fructose, weight gain, and the insulin resistance syndrome</a></li><li id="footnote_3_563" class="footnote"><a href="http://www.ajcn.cnfindpark.cn/cgi/content/abstract/79/4/537">Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity</a></li><li id="footnote_4_563" class="footnote"><a href="http://jcem.endojournals.org/cgi/content/abstract/89/6/2963">Dietary Fructose Reduces Circulating Insulin and Leptin, Attenuates Postprandial Suppression of Ghrelin, and Increases Triglycerides in Women</a></li><li id="footnote_5_563" class="footnote"><a href="http://www.ajcn.org/cgi/content/abstract/50/5/1008">Day-long glucose, insulin, and fructose responses of hyperinsulinemic and nonhyperinsulinemic men adapted to diets containing either fructose or high-amylose cornstarch</a></li><li id="footnote_6_563" class="footnote"><a href="http://www.ajcn.org/cgi/content/abstract/86/6/1586">No differences in satiety or energy intake after high-fructose corn syrup, sucrose, or milk preloads</a></li><li id="footnote_7_563" class="footnote"><a href="http://www.ajcn.org/cgi/content/abstract/88/6/1738S?ijkey=51a6eb2a2a2308a265762245d4dc6f538a555c36&amp;keytype2=tf_ipsecsha">High-fructose corn syrup, energy intake, and appetite regulation</a></li><li id="footnote_8_563" class="footnote"><a href="http://www.ajcn.cnfindpark.cn/cgi/content/abstract/86/5/1354">Effects of glucose-to-fructose ratios in solutions on subjective satiety, food intake, and satiety hormones in young men</a></li><li id="footnote_9_563" class="footnote"><a href="http://jn.nutrition.org/cgi/content/abstract/139/6/1242S">The Effect of High-Fructose Corn Syrup Consumption on Triglycerides and Uric Acid</a></li><li id="footnote_10_563" class="footnote"><a href="http://ajcn.cnfindpark.cn/cgi/content/abstract/87/5/1194">Twenty-four-hour endocrine and metabolic profiles following consumption of high-fructose corn syrup-, sucrose-, fructose-, and glucose-sweetened beverages with meals</a></li><li id="footnote_11_563" class="footnote"><a href="http://www.ncbi.nlm.nih.gov/pubmed/17234503">Effects of high-fructose corn syrup and sucrose consumption on circulating glucose, insulin, leptin, and ghrelin and on appetite in normal-weight women</a></li><li id="footnote_12_563" class="footnote"><a href="http://cat.inist.fr/?aModele=afficheN&amp;cpsidt=18373945">A 4-wk high-fructose diet alters lipid metabolism without affecting insulin sensitivity or ectopic lipids in healthy humans</a></li><li id="footnote_13_563" class="footnote"><a href="http://www.ajcn.org/cgi/content/full/79/5/774?ijkey=cJSxz0rjkfs9s&amp;keytype=ref&amp;siteid=ajcn">Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment</a></li><li id="footnote_14_563" class="footnote"><a href="http://www.nutritionandmetabolism.com/content/2/1/5" target="_blank">Fructose, insulin resistance, and metabolic dyslipidemia</a></li><li id="footnote_15_563" class="footnote"><a href="http://www.nutritionandmetabolism.com/content/2/1/5#B7">Fructose, insulin resistance, and metabolic dyslipidemia</a></li><li id="footnote_16_563" class="footnote"><a href="http://www.health.gov/dietaryguidelines/dga2005/document/html/chapter7.htm" target="_blank">Carbohydrates</a></li><li id="footnote_17_563" class="footnote"><a href="http://www.ncbi.nlm.nih.gov/pubmed/12324283?dopt=Abstract&amp;holding=f1000,f1000m,isrctn">Sucrose compared with artificial sweeteners: different effects on ad libitum food intake and body weight after 10 wk of supplementation in overweight subjects</a></li></ol>]]></content:encoded>
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		<item>
		<title>What causes kidney stones and can you prevent them?</title>
		<link>http://justthescience.com/archives/424</link>
		<comments>http://justthescience.com/archives/424#comments</comments>
		<pubDate>Thu, 15 Oct 2009 00:29:22 +0000</pubDate>
		<dc:creator></dc:creator>
				<category><![CDATA[Personal Health]]></category>
		<category><![CDATA[animal protein]]></category>
		<category><![CDATA[apple juice]]></category>
		<category><![CDATA[beer]]></category>
		<category><![CDATA[bimodal]]></category>
		<category><![CDATA[caffeinated coffee]]></category>
		<category><![CDATA[calcium compounds]]></category>
		<category><![CDATA[chronic diseases]]></category>
		<category><![CDATA[correlation]]></category>
		<category><![CDATA[decaffeinated coffee]]></category>
		<category><![CDATA[diet]]></category>
		<category><![CDATA[dietary calcium]]></category>
		<category><![CDATA[evolving consensus]]></category>
		<category><![CDATA[family history]]></category>
		<category><![CDATA[grapefruit juice]]></category>
		<category><![CDATA[Kidney Stones]]></category>
		<category><![CDATA[micro-bacteria]]></category>
		<category><![CDATA[phylate]]></category>
		<category><![CDATA[re-occurence]]></category>
		<category><![CDATA[sucrose]]></category>
		<category><![CDATA[supersaturation]]></category>
		<category><![CDATA[tea]]></category>
		<category><![CDATA[treatment resistant]]></category>
		<category><![CDATA[uric acid]]></category>
		<category><![CDATA[variance between sexes]]></category>
		<category><![CDATA[vitamin B6]]></category>
		<category><![CDATA[vitamin C]]></category>
		<category><![CDATA[vitamin D]]></category>
		<category><![CDATA[water intake]]></category>
		<category><![CDATA[weight]]></category>
		<category><![CDATA[wine]]></category>

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		<description><![CDATA[Kidney stones will effect around 5 percent of people in at some point in their life, and the rate is growing with time (Parmar 2004). 1   Significant variation of occurrence exists between sexes; men develop stones twice as often as women at an average age of 30 while for women average age is bimodal with peaks [...]]]></description>
			<content:encoded><![CDATA[<p>Kidney stones will effect around 5 percent of people in at some point in their life, and the rate is growing with time (Parmar 2004). <sup><a href="http://justthescience.com/archives/424#footnote_0_424" id="identifier_0_424" class="footnote-link footnote-identifier-link" title="Kidney stones">1</a></sup>   Significant variation of occurrence exists between sexes; men develop stones twice as often as women at an average age of 30 while for women average age is bimodal with peaks at 35 and 55 (Parmar 2004).<sup><a href="http://justthescience.com/archives/424#footnote_1_424" id="identifier_1_424" class="footnote-link footnote-identifier-link" title="Kidney stones">2</a></sup>   Once you have had one, you also have a very high chance of having another one as there is a re-occurrence rate of 50% over five years  (Borghi <em>et al</em> 1996).<sup><a href="http://justthescience.com/archives/424#footnote_2_424" id="identifier_2_424" class="footnote-link footnote-identifier-link" title="Urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomized prospective study">3</a></sup>  Although there is still somewhat of an evolving consensus around what the main cause is, literature points to treatment resistant micro-bacteria  (Çiftçioglu <em>et al</em> 1999) that combines with urine supersaturated with calcium compounds and uric acid (contributed by an individual&#8217;s diet), creating the kidney stone (Kajander <em>et al</em> 2003). <sup><a href="http://justthescience.com/archives/424#footnote_3_424" id="identifier_3_424" class="footnote-link footnote-identifier-link" title="Nanobacteria: An infectious cause for kidney stone formation">4</a></sup> <sup><a href="http://justthescience.com/archives/424#footnote_4_424" id="identifier_4_424" class="footnote-link footnote-identifier-link" title="Characteristics of nanobacteria and their possible role in stone formation">5</a></sup></p>
<p>An individual&#8217;s weight and family history have both been demonstrated to have a positive correlation with his or her risk of getting kidney stones (Taylor <em>et al</em> 2005) (Curhan <em>et al</em> 1997). <sup><a href="http://justthescience.com/archives/424#footnote_5_424" id="identifier_5_424" class="footnote-link footnote-identifier-link" title="Obesity, Weight Gain, and the Risk of Kidney Stones">6</a></sup> <sup><a href="http://justthescience.com/archives/424#footnote_6_424" id="identifier_6_424" class="footnote-link footnote-identifier-link" title="Family history and risk of kidney stones">7</a></sup>  However, lack of daily water intake has been demonstrated to be the greatest risk factor, and increasing one&#8217;s daily water intake is an easily preventative measure one can take to avoid getting stone&#8217;s in the first place (Borghi <em>et al</em> 1996). <sup><a href="http://justthescience.com/archives/424#footnote_7_424" id="identifier_7_424" class="footnote-link footnote-identifier-link" title="Urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomized prospective study">8</a></sup>  Drinking at least 2.5 liters of water per day has been shown to change the consistency of urine, lowering it&#8217;s saturation level of calcium compounds, thereby preventing supersaturation and it&#8217;s associated buildups (Borghi <em>et al</em> 1996).<sup><a href="http://justthescience.com/archives/424#footnote_8_424" id="identifier_8_424" class="footnote-link footnote-identifier-link" title="Urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomized prospective study">9</a></sup>  This alone has been found to reduce reoccurred rates of kidney stones from 50% to 20% over a five year period (Borghi <em>et al</em> 1996). <sup><a href="http://justthescience.com/archives/424#footnote_9_424" id="identifier_9_424" class="footnote-link footnote-identifier-link" title="Urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomized prospective study">10</a></sup></p>
<p>Intake of other fluids have also been found to decrease instances of kidney stones in both sexes.  A study by Curhan <em>et al</em> (1998) found the following percentage of occurrence reductions in women for each 240-mL (8-oz) daily serving of the following fluids: caffeinated coffee &#8211; 10%, decaffeinated coffee &#8211; 9%, tea &#8211; 8%, and wine &#8211; 59%.<sup><a href="http://justthescience.com/archives/424#footnote_10_424" id="identifier_10_424" class="footnote-link footnote-identifier-link" title="Beverage Use and Risk for Kidney Stones in Women">11</a></sup>  In contrast, a 44% increase in risk was seen for each 240-mL serving of grapefruit juice consumed daily (Curhan <em>et al</em> 1998).   In men the risk of stone formation decreased by the following percentages for each 240-ml (8-oz) daily serving of the following fluids:  caffeinated coffee 10%, decaffeinated coffee &#8211; 10%, tea &#8211; 14%,  beer &#8211; 21%, and wine &#8211; 39%. In contrast, a risk increased 35% for comparable servings of apple juice and 37% for grapefruit juice (Curhan <em>et al</em> 1996).<sup><a href="http://justthescience.com/archives/424#footnote_11_424" id="identifier_11_424" class="footnote-link footnote-identifier-link" title="Prospective Study of Beverage Use and the Risk of Kidney Stones">12</a></sup></p>
<p>Reducing one&#8217;s consumption of animal protein to less than 52g per day has also been shown to lower one&#8217;s risk of specific types of kidney stones (Breslau <em>et al</em> 1988).<sup><a href="http://justthescience.com/archives/424#footnote_12_424" id="identifier_12_424" class="footnote-link footnote-identifier-link" title="Relationship of Animal Protein-Rich Diet to Kidney Stone Formation and Calcium Metabolism">13</a></sup>  Increasing dietary calcium has been shown to lower risk for kidney stones in women (Borghi <em>et al</em> 2002) and men (Curhan <em>et al</em> 1993) and lowering your salt intake to less than 800 mg per day combined with lower intake of animal protein lowers men&#8217;s risk of re-occurrence by 18% (Borghi <em>et al 2002</em>).<sup><a href="http://justthescience.com/archives/424#footnote_13_424" id="identifier_13_424" class="footnote-link footnote-identifier-link" title="Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria">14</a></sup>  Also, vitamin B6 in doses of &gt;40mg/day has been found to reduce incidences of kidney stones in women (Curhan <em>et al</em> 1999).<sup><a href="http://justthescience.com/archives/424#footnote_14_424" id="identifier_14_424" class="footnote-link footnote-identifier-link" title="Intake of Vitamins B6 and C and the Risk of Kidney Stones in Women">15</a></sup><sup><a href="http://justthescience.com/archives/424#footnote_15_424" id="identifier_15_424" class="footnote-link footnote-identifier-link" title="A Prospective Study of Dietary Calcium and Other Nutrients and the Risk of Symptomatic Kidney Stones">16</a></sup>  A recent study by Taylor <em>et </em>al (2004) determined that in men: sodium phosphorus, sucrose, phytate, vitamin B6, vitamin D, and supplemental calcium were not independently associated with risk for first time instances, while magnesium intake decreases and total vitamin C intake seems to increase the risk of kidney stones (Taylor <em>et al</em> 2004).<sup><a href="http://justthescience.com/archives/424#footnote_16_424" id="identifier_16_424" class="footnote-link footnote-identifier-link" title="Dietary Factors and the Risk of Incident Kidney Stones in Men: New Insights after 14 Years of Follow-up">17</a></sup>  While this research may appear to contradict the previous study by Borghi <em>et al</em> (2002), this study examined the combination of reduced salt and animal protein, which suggests that reducing animal protein consumption is a more important dietary change to aid in reduced kidney stone risk.<sup><a href="http://justthescience.com/archives/424#footnote_17_424" id="identifier_17_424" class="footnote-link footnote-identifier-link" title="Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria">18</a></sup></p>
<ol class="footnotes"><li id="footnote_0_424" class="footnote"><a href="http://www.bmj.com/cgi/content/full/328/7453/1420?etoc#REF2">Kidney stones</a></li><li id="footnote_1_424" class="footnote"><a href="http://www.bmj.com/cgi/content/full/328/7453/1420?etoc#REF2">Kidney stones</a></li><li id="footnote_2_424" class="footnote"><a href="http://www.ncbi.nlm.nih.gov/pubmed/8583588?dopt=Abstract">Urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomized prospective study</a></li><li id="footnote_3_424" class="footnote"><a href="http://www.nature.com/ki/journal/v56/n5/abs/4491112a.html">Nanobacteria: An infectious cause for kidney stone formation</a></li><li id="footnote_4_424" class="footnote"><a href="http://www.springerlink.com/content/5kch22gexykuqbln/">Characteristics of nanobacteria and their possible role in stone formation</a></li><li id="footnote_5_424" class="footnote"><a href="http://jama.ama-assn.org/cgi/content/abstract/293/4/455">Obesity, Weight Gain, and the Risk of Kidney Stones</a></li><li id="footnote_6_424" class="footnote"><a href="http://jasn.asnjournals.org/cgi/content/abstract/8/10/1568">Family history and risk of kidney stones</a></li><li id="footnote_7_424" class="footnote"><a href="http://www.ncbi.nlm.nih.gov/pubmed/8583588?dopt=Abstract">Urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomized prospective study</a></li><li id="footnote_8_424" class="footnote"><a href="http://www.ncbi.nlm.nih.gov/pubmed/8583588?dopt=Abstract">Urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomized prospective study</a></li><li id="footnote_9_424" class="footnote"><a href="http://www.ncbi.nlm.nih.gov/pubmed/8583588?dopt=Abstract">Urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomized prospective study</a></li><li id="footnote_10_424" class="footnote"><a href="http://www.annals.org/cgi/content/abstract/128/7/534">Beverage Use and Risk for Kidney Stones in Women</a></li><li id="footnote_11_424" class="footnote"><a href="http://aje.oxfordjournals.org/cgi/content/abstract/143/3/240">Prospective Study of Beverage Use and the Risk of Kidney Stones</a></li><li id="footnote_12_424" class="footnote"><a href="http://jcem.endojournals.org/cgi/content/abstract/66/1/140">Relationship of Animal Protein-Rich Diet to Kidney Stone Formation and Calcium Metabolism</a></li><li id="footnote_13_424" class="footnote"><a href="http://www.ncbi.nlm.nih.gov/pubmed/11784873?dopt=Abstract" target="_blank">Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria</a></li><li id="footnote_14_424" class="footnote"><a href="http://jasn.asnjournals.org/cgi/content/abstract/10/4/840">Intake of Vitamins B6 and C and the Risk of Kidney Stones in Women</a></li><li id="footnote_15_424" class="footnote"><a href="http://content.nejm.org/cgi/content/abstract/328/12/833">A Prospective Study of Dietary Calcium and Other Nutrients and the Risk of Symptomatic Kidney Stones</a></li><li id="footnote_16_424" class="footnote"><a href="http://jasn.asnjournals.org/cgi/content/abstract/15/12/3225">Dietary Factors and the Risk of Incident Kidney Stones in Men: New Insights after 14 Years of Follow-up</a></li><li id="footnote_17_424" class="footnote"><a href="http://www.ncbi.nlm.nih.gov/pubmed/11784873?dopt=Abstract" target="_blank">Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria</a></li></ol>]]></content:encoded>
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